The Top 5 Countries With the Highest Number of People Living With HIV

  Country People Living with HIV AIDS HIV prevalence rate
1 South Africa 7.8 million 20.4%
2 Nigeria 3.8 million 1.4%
3 Mozambique 2.2 million 7.6%
4 India 2.1 million 0.2%
5 Uganda 1.4 million 5.7%
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 Special Report


Global HIV Statistics 2021: A Top 5 Snapshot

According to the latest data, an estimated 38.4 million people worldwide were living with HIV in 2021. This figure, which ranges from 33.9 million to 43.8 million, highlights the ongoing impact of the HIV/AIDS epidemic.

Tragically, 1.5 million individuals became newly infected with HIV in 2021. This statistic serves as a stark reminder that despite progress in prevention efforts, the virus continues to spread at an alarming rate. The range for new infections is estimated to be between 1.1 million and 2.0 million. Furthermore, AIDS-related illnesses claimed the lives of approximately 650,000 individuals in 2021. These devastating numbers underscore the urgent need for improved access to treatment, care, and support for those affected.

On a positive note, 28.7 million people were able to access antiretroviral therapy in 2021. This medical intervention plays a crucial role in managing the virus and improving the quality of life for those living with HIV. Since the start of the epidemic, a staggering 84.2 million people have become infected with HIV worldwide. This number, ranging from 64.0 million to 113.0 million, highlights the long-standing impact of the disease on global health.

Finally, the number of deaths resulting from AIDS-related illnesses since the beginning of the epidemic is estimated to be 40.1 million people. This sobering figure, ranging from 33.6 million to 48.6 million, serves as a reminder of the lives lost and the ongoing challenges we face in the fight against HIV/AIDS.

These statistics paint a complex picture of the global HIV/AIDS situation in 2021. While progress has been made in certain areas, there is still much work to be done to prevent new infections, increase access to treatment, and provide support for those affected by the virus. Together, we must continue to raise awareness, promote education, and advocate for the resources needed to end the HIV/AIDS epidemic once and for all.

Comparing Past Global HIV Statistics

In 2008 some 1,200 children were infected with HIV every day. 2,500 young people (15-24) and 3,700 adults over 25 years of age were infected with the HIV virus every single day of the year. That translated to 430,000 children, 920,000 young people and 1,340,000 adults infected yearly. However the global percentage of adults living with HIV has leveled off since 2000.

In 2008 there were 2,100,000 children, 5,000,000 young people and 26,300,000 adults living with HIV across the globe. The vast majority of these people live in Sun Saharan Africa (about 22 million). Sub-Saharan Africa remains the region most heavily affected by HIV, accounting for 67% of all people living with HIV and for 75% of AIDS deaths in 2007. However, some of the most worrisome increases in new infections are now occurring in populous countries in other regions, such as Indonesia, the Russian Federation, and various high-income countries.

The estimated spending for HIV/AIDS prevention, care and support in low and middle income countries (public and private sources) was 10 billion dollars which includes domestic (government) spending, estimated out-of-pocket spending by directly affected individuals and their families, and funding from bilateral donors, multilateral agencies, and the private sectors (for the year 2007).

There were 1.1 million people living with AIDS in the United States in 2006. In the same year there were 56,300 new infections. 49% of these new infection were African American which represented 12% of the U.S. population. 30% of whites were infected and 19% of Latinos which represented 66% and 15% of the U.S. population respectively.

HIV, or the Human immunodeficiency virus, is the virus that causes AIDS. HIV can be transmitted through infected blood, semen, vaginal secretions, breast milk, and during pregnancy or delivery. HIV destroys certain white blood cells called CD4+ T cells. These cells are critical to the normal function of the human immune system, which defends the body against illness. When HIV weakens the immune system, a person is more susceptible to developing a variety of cancers and becoming infected with viruses, bacteria and parasites. The disease has four stages: primary or acute HIV infection, asymptomatic, symptomatic, and advanced HIV disease or AIDS.

Top 5 facts sources: UNAIDS, Kaiser Family Foundation. (All figures are in U.S. dollars.)
Tags: Health Statistics, Top 5 Highest, AIDS & HIV Statistics

Sources:  UNAIDS 2022, UNAIDS HIV Estimates are from 1990 to present.

List Notes: Data is the Top 5 countries with the Highest estimated number of people living with HIV AIDS for the year 2021. People living with HIV AIDS are estimated adults (15+). Prevalence rate is the percentage of the population estimated adults (15+).
Countries With the Highest Number of People Living With HIV

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